The clinical laboratory is an indispensable and important part of the process of diagnosing the patient's disease. The clinical laboratory must be able to provide the patient with accurate, fast, and a wider range of test items to help the doctor make an accurate diagnosis to facilitate the treatment of medical education. Web collection. The development and use of more advanced inspection techniques are the constant pursuit of manufacturers and inspectors. At present, new technologies are mainly concentrated in the following aspects.
Immunoassay technology currently uses chemiluminescence, fluorescence measurement, radionuclide labeling, coupled particle scattering, and other technologies to enable early prediction of various diseases such as cardiovascular diseases, tumors, and infectious diseases. The instrument can detect the soluble and cellular components in the blood, and simultaneously perform clinical chemistry, immunoassay, and hematology tests.
The gene chip technology uses a DNA chip consisting of DNA probes to classify and diagnose cancer by detecting differences in gene expression. Different biological gene chip technologies can enter molecular and protein levels, and can be used for disease susceptibility prediction, infectious disease pathogens and drug resistance detection, individual drug sensitivity testing, etc.; at the same time in law, drug design, environmental protection, agriculture, biological sciences Other aspects can also play a role.
As a result of the application of electronic technology, the clinical testing technology and instrument performance have achieved unprecedented development, the degree of laboratory automation has been greatly improved, testing items have gradually increased, and the detection speed and accuracy have increased, mainly based on the instrument's processing efficiency, data accuracy, and repeatability. Stability, operating costs, menu design, labor utilization, and scope of use. In clinical application, in addition to general clinical testing items, according to the clinical needs of equipment, keeping pace with the pace of medical development should not be ignored, often the level of clinical testing directly affects the level of clinical diagnosis and treatment. Understand and understand the performance quality of a wide range of experimental instruments, pay attention to its development trends and characteristics, so that limited funds can be reasonably applied to the medical education network to collect and collate. At present, the new features of clinical testing instruments are roughly:
1 Instant inspection of various small-scale inspection instruments has made the process of submitting inspections-inspection-reporting of the original cumbersome collection specimens simple, and it has become a trend of development, such as blood glucose meter, oximeter, and blood gas, which is compact, portable, light, fast, and inexpensive. Analyzers, etc., have the characteristics of simple operation, non-invasive or minimally invasive. Concentrate multiple test items on a small instrument to facilitate emergency examination. For example, the AVL-OMNI multi-parameter analyzer can provide blood gas, electrolytes, blood oxygen, hemoglobin, biochemical measurements, and can store 50,000 copies for clinical use. Test results. Miniaturized, on-time instrumentation is used not only for first aid, intensive care, surgery, but also for community or home care.
2 Fully Automated In the 1980s, fully automated clinical laboratory technology emerged in Japan. Sample transport systems and automated control technologies were used. Inspectors only needed to place specimens on conveyor belts. Analytical instruments could work according to well-designed procedures. Inspectors did not Re-exposure to specimens, automatic sampling, and automatic reporting reduce the chances of using infected personnel and save labor. For example, the Aeroset model can complete 1.5 million inspections per year, examine 59 projects, and complete 2,000 inspections per hour. More than 70% of the hospitals of the National University of Japan are equipped with automation systems of different sizes. Due to the high cost of equipment for automatic inspection, it has limited the development of small and medium-sized hospitals and economically underdeveloped areas. At present, there are not many hospitals equipped with automatic clinical inspection systems in China.
3 modular design According to the needs of the modular assembly of the task module is to adapt to the limited use of limited funds, a new type of design concept. The modules can form independent working units and can also be combined to form a fully automatic system. The design can be closely combined to form a high-quality, multi-functional inspection system, enabling an instrument to measure routine, special biochemical, drug treatment, drug abuse, and special Protein, immunity and other items can also be added to various components to expand their functionality. It has the characteristics of small size, multiple testing items, high automation, and saving of funds, etc. It is used in large and medium-sized hospitals. Compared with large investment laboratories, modular access systems are more convenient, flexible, economical and practical. 4 Design robotization From the input of specimens, barcode input, complete detection, data storage output, connection to the network, the work process completed by the original manual is completely completed by the instrument at one time, and the computer-controlled robot arm and data processing and analysis system can be accurate To complete various tasks faster. The instrument can be automatically checked on a regular basis to eliminate human factors and non-standard interference. The results can be easily stored, reduce errors, and shorten the report time.
Pay attention to environmental protection inspection personnel in the work process are very vulnerable to bacterial infections, the use of vacuum blood collection needles and automated detection equipment can reduce pollution and improve efficacy. The chemical reagents used in the test are likely to contaminate the water source and use dry reagents to reduce the contamination of the water. The competition in the medical service market has exacerbated the upgrading of equipment and equipment. Manufacturers are also constantly looking for new business opportunities. Competition in the medical instrument market is a competition. Only the pursuit of new technologies can continuously occupy the new market commanding heights. Automation, high intelligence, new design combinations, low cost, and low pollution are still the directions for the development of clinical laboratory instruments.
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